TADA2L Antibody
| Code | Size | Price |
|---|
| PSI-58-092-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein, TADA2A, TADA2L
Application Note:
For WB starting dilution is: 1:1000
Background:
Many DNA-binding transcriptional activator proteins
enhance the initiation rate of RNA polymerase II-mediated gene
transcription by interacting functionally with the general
transcription machinery bound at the basal promoter. Adaptor
proteins are usually required for this activation, possibly to
acetylate and destabilize nucleosomes, thereby relieving chromatin
constraints at the promoter. The protein encoded by this gene is a
transcriptional activator adaptor and has been found to be part of
the PCAF histone acetylase complex. Several alternatively spliced
transcript variants encoding different isoforms of this gene have
been described, but the full-length nature of some of these
variants has not been determined.
Background References:
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Yang, M., et al. Cancer Biol. Ther. 7(1):120-128(2008)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Qian, C., et al. Nat. Struct. Mol. Biol. 12(12):1078-1085(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This TADA2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human TADA2L.
NCBI Gene ID #:
6871
NCBI Official Name:
Transcriptional adapter 2-alpha
NCBI Official Symbol:
TADA2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
O75478
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75478
User NOte:
Optimal dilutions for each application to be determined by the researcher.