HAT1 Antibody
| Code | Size | Price |
|---|
| PSI-57-822-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1, HAT1, KAT1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a type B histone
acetyltransferase (HAT) that is involved in the rapid acetylation
of newly synthesized cytoplasmic histones, which are in turn
imported into the nucleus for de novo deposition onto nascent DNA
chains. Histone acetylation, particularly of histone H4, plays an
important role in replication-dependent chromatin assembly.
Specifically, this HAT can acetylate soluble but not nucleosomal
histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A
at lysine 5. Alternatively spliced transcript variants have been
identified for this gene.
Background References:
- Saade, E., et al. Proteomics 9(21):4934-4943(2009)
- Miyamoto, N., et al. J. Biol. Chem. 283(26):18218-18226(2008)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This HAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HAT1.
NCBI Gene ID #:
8520
NCBI Official Name:
Histone acetyltransferase type B catalytic subunit
NCBI Official Symbol:
HAT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
O14929
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O14929
User NOte:
Optimal dilutions for each application to be determined by the researcher.