GCN5 Antibody

ProSci
Product Code: PSI-55-421
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-421-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-GCN5 Antibody in 293 cell line lysates (35ug/lane)

Western blot analysis of anti-GCN5 Antibody in 293 cell line lysates (35ug/lane)

Further Information

Additional Names:
Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5
Application Note:
For WB starting dilution is: 1:1000
Background:
GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. This protein has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles.
Background References:
  • Sabo,A., Mol. Cell. Biol. 28 (7), 2201-2212 (2008)
  • Wiper-Bergeron,N., Proc. Natl. Acad. Sci. U.S.A. 104 (8), 2703-2708 (2007)
  • Oishi,H., J. Biol. Chem. 281 (1), 20-26 (2006)
  • Kikuchi,H., Gene 347 (1), 83-97 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This GCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human GCN5.
NCBI Gene ID #:
2648
NCBI Official Name:
Histone acetyltransferase KAT2A
NCBI Official Symbol:
KAT2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
94 kDa
Protein Accession #:
Q92830
Protein GI Number:
209572743
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
Q92830
User NOte:
Optimal dilutions for each application to be determined by the researcher.