HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody
| Code | Size | Price |
|---|
| PSI-60-716-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone H2B type 1-J, Histone H2B1, Histone H2Br, H2B/r, HIST1H2BJ, H2BFR
Application Note:
For WB starting dilution is: 1:1000
Background:
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the histone microcluster on chromosome 6p21.33. [provided
by RefSeq].
Background References:
- Shi, J., et al. Nature 460(7256):753-757(2009)
- Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009)
- Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
- Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Monkey, Mouse
Immunogen:
This HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HIST1H2BJ/HIST1H2BK/HIST3H2BB.
NCBI Gene ID #:
8970
NCBI Official Name:
Histone H2B type 1-J
NCBI Official Symbol:
HIST1H2BJ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
P06899
Protein GI Number:
7404367
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P06899
User NOte:
Optimal dilutions for each application to be determined by the researcher.