H2BFS Antibody

ProSci
Product Code: PSI-59-982
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-982-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: WiDr whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: WiDr whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Histone H2B type F-S, Histone H2Bs, H2B/s, H2BFS
Application Note:
For WB starting dilution is: 1:1000
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This H2BFS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human H2BFS.
NCBI Gene ID #:
102724334
NCBI Official Name:
Histone H2B type F-S
NCBI Official Symbol:
H2BFS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
P57053
Protein GI Number:
9973351
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P57053
User NOte:
Optimal dilutions for each application to be determined by the researcher.