DACH2 Antibody
| Code | Size | Price |
|---|
| PSI-56-944-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dachshund homolog 2, Dach2, DACH2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is one of two genes which encode a protein
similar to the Drosophila protein dachshund, a transcription factor
involved in cell fate determination in the eye, limb and genital
disc of the fly. The encoded protein contains two characteristic
dachshund domains: an N-terminal domain responsible for DNA binding
and a C-terminal domain responsible for protein-protein
interactions. This gene is located on the X chromosome and is
subject to inactivation by DNA methylation. The encoded protein may
be involved in regulation of organogenesis and myogenesis, and may
play a role in premature ovarian failure. Multiple transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Styrkarsdottir, U., et al. Nat. Genet. 41(1):15-17(2009)
- Poulin, F., et al. Genomics 85(6):774-781(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human DACH2.
NCBI Gene ID #:
117154
NCBI Official Name:
Dachshund homolog 2
NCBI Official Symbol:
DACH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q96NX9
Protein GI Number:
44887818
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96NX9
User NOte:
Optimal dilutions for each application to be determined by the researcher.