SNUPN Antibody
| Code | Size | Price |
|---|
| PSI-58-602-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Snurportin-1, RNA U transporter 1, SNUPN, RNUT1, SPN1
Application Note:
For WB starting dilution is: 1:1000
Background:
The nuclear import of the spliceosomal snRNPs U1, U2, U4
and U5, is dependent on the presence of a complex nuclear
localization signal. The latter is composed of the
5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U
snRNA and the Sm core domain. The protein encoded by this gene
interacts specifically with m3G-cap and functions as an
snRNP-specific nuclear import receptor. Alternatively spliced
transcript variants encoding the same protein have been identified
for this gene.
Background References:
- Goette, M., et al. Biophys. J. 97(2):581-589(2009)
- Monecke, T., et al. Science 324(5930):1087-1091(2009)
- Ospina, J.K., et al. Mol. Biol. Cell 16(10):4660-4671(2005)
- Stelzl, U., et al. Cell 122(6):957-968(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SNUPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human SNUPN.
NCBI Gene ID #:
10073
NCBI Official Name:
Snurportin-1
NCBI Official Symbol:
SNUPN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
O95149
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O95149
User NOte:
Optimal dilutions for each application to be determined by the researcher.