TAF1A Antibody
| Code | Size | Price |
|---|
| PSI-58-292-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
TATA box-binding protein-associated factor RNA polymerase I subunit A, RNA polymerase I-specific TBP-associated factor 48 kDa, TAFI48, TATA box-binding protein-associated factor 1A, TBP-associated factor 1A, Transcription factor SL1, Transcription initiation factor SL1/TIF-IB subunit A, TAF1A
Application Note:
For WB starting dilution is: 1:1000
Background:
Initiation of transcription by RNA polymerase I requires
the formation of a complex composed of the TATA-binding protein
(TBP) and three TBP-associated factors (TAFs) specific for RNA
polymerase I. This complex, known as SL1, binds to the core
promoter of ribosomal RNA genes to position the polymerase properly
and acts as a channel for regulatory signals. This gene encodes the
smallest SL1-specific TAF. Two transcripts encoding different
isoforms have been identified.
Background References:
- Greco-Stewart, V.S., et al. Virology 386(1):12-15(2009)
- Yamamoto, K., et al. Mol. Cell. Biol. 24(14):6338-6349(2004)
- Dynes, J.L., et al. J. Biochem. 135(3):429-438(2004)
- Hirschler-Laszkiewicz, I., et al. J. Biol. Chem. 278(21):18953-18959(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TAF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human TAF1A.
NCBI Gene ID #:
9015
NCBI Official Name:
TATA box-binding protein-associated factor RNA polymerase I subunit A
NCBI Official Symbol:
TAF1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q15573
Protein GI Number:
74739864
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15573
User NOte:
Optimal dilutions for each application to be determined by the researcher.