SPANXE Antibody
| Code | Size | Price |
|---|
| PSI-60-307-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sperm protein associated with the nucleus on the X chromosome E, Nuclear-associated protein SPAN-Xe, SPANX-E, SPANX family member E, SPANXE
Application Note:
For WB starting dilution is: 1:1000
Background:
Temporally regulated transcription and translation of
several testis-specific genes is required to initiate the series of
molecular and morphological changes in the male germ cell lineage
necessary for the formation of mature spermatozoa. This gene is a
member of the SPANX family of cancer/testis-associated genes, which
are located in a cluster on chromosome X. The SPANX genes encode
differentially expressed testis-specific proteins that localize to
various subcellular compartments. This particular gene encodes a
sperm protein that contains a consensus nuclear localization signal
but, although a role in spermatogenesis is suggested, the specific
function of this family member has not yet been determined.
Background References:
- Hansen, S., et al. Syst Biol Reprod Med 55, 18-26 (2010) :
- Kouprina, N., et al. Genome Res. 15(11):1477-1486(2005)
- Zendman, A.J., et al. Gene 309(2):125-133(2003)
- Westbrook, V.A., et al. Biol. Reprod. 64(1):345-358(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPANXE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of human SPANXE.
NCBI Gene ID #:
64663
NCBI Official Name:
Sperm protein associated with the nucleus on the X chromosome E
NCBI Official Symbol:
SPANXE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
11 kDa
Protein Accession #:
Q8TAD1
Protein GI Number:
85543354
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TAD1
User NOte:
Optimal dilutions for each application to be determined by the researcher.