WDR4 Antibody
| Code | Size | Price |
|---|
| PSI-59-281-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}, WD repeat-containing protein 4 {ECO:0000255|HAMAP-Rule:MF_03056}, WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the WD repeat protein
family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),
which may facilitate formation of heterotrimeric or multiprotein
complexes. Members of this family are involved in a variety of
cellular processes, including cell cycle progression, signal
transduction, apoptosis, and gene regulation. This gene is excluded
as a candidate for a form of nonsyndromic deafness (DFNB10), but is
still a candidate for other disorders mapped to 21q22.3 as well as
for the development of Down syndrome phenotypes. Two transcript
variants encoding the same protein have been found for this gene.
Background References:
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
- Cartlidge, R.A., et al. EMBO J. 24(9):1696-1705(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This WDR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human WDR4.
NCBI Gene ID #:
10785
NCBI Official Name:
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}
NCBI Official Symbol:
WDR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P57081
Protein GI Number:
20141943
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P57081
User NOte:
Optimal dilutions for each application to be determined by the researcher.