GLP1 Antibody
| Code | Size | Price |
|---|
| PSI-61-954-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
GATA-type zinc finger protein 1, GATA-like protein 1, GLP-1, ZGLP1, GLP1
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
Glucagon is initially synthesised as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.
Background References:
- Sanz, C., et al. Am. J. Physiol. Endocrinol. Metab. 298 (3), E634-E643 (2010) :
- Brown, R.J., et al. Diabetes Care 32(12):2184-2186(2009)
- Li, S., et al. Dev. Biol. 301(1):106-116(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GLP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the Central region of human GLP1.
NCBI Gene ID #:
100125288
NCBI Official Name:
GATA-type zinc finger protein 1
NCBI Official Symbol:
ZGLP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
P0C6A0
Protein GI Number:
166990464
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P0C6A0
User NOte:
Optimal dilutions for each application to be determined by the researcher.