GTF2I Antibody
Code | Size | Price |
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PSI-59-657-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
General transcription factor II-I, GTFII-I, TFII-I, Bruton tyrosine kinase-associated protein 135, BAP-135, BTK-associated protein 135, SRF-Phox1-interacting protein, SPIN, Williams-Beuren syndrome chromosomal region 6 protein, GTF2I, BAP135, WBSCR6
Application Note:
For IF starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This gene encodes a multifunctional phosphoprotein with
roles in transcription and signal transduction. It is deleted in
Williams-Beuren syndrome, a multisystem developmental disorder
caused by the deletion of contiguous genes at chromosome 7q11.23.
Alternative splicing results in multiple transcript variants.
Related pseudogenes have been identified on chromosomes 7, 13 and
21.
Background References:
- Antonell, A., et al. J. Med. Genet. 47(5):312-320(2010)
- Lazebnik, M.B., et al. J. Biol. Chem. 284(52):36234-36239(2009)
- Sacristan, C., et al. Eur. J. Immunol. 39(9):2584-2595(2009)
- Makeyev, A.V., et al. Gene 433 (1-2), 16-25 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This GTF2I antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the N-terminal region of human GTF2I.
NCBI Gene ID #:
2969
NCBI Official Name:
General transcription factor II-I
NCBI Official Symbol:
GTF2I
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
P78347
Protein GI Number:
17865459
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P78347
User NOte:
Optimal dilutions for each application to be determined by the researcher.