SEPN1 Antibody
| Code | Size | Price |
|---|
| PSI-56-434-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Selenoprotein N, SelN, SEPN1, SELN
Application Note:
For IHC-P starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This gene encodes a selenoprotein, which contains a
selenocysteine (Sec) residue at its active site. The selenocysteine
is encoded by the UGA codon that normally signals translation
termination. The 3' UTR of selenoprotein genes have a common
stem-loop structure, the sec insertion sequence (SECIS), that is
necessary for the recognition of UGA as a Sec codon rather than as
a stop signal. Mutations in this gene cause the classical phenotype
of multiminicore disease and congenital muscular dystrophy with
spinal rigidity and restrictive respiratory syndrome. Two
alternatively spliced transcript variants encoding distinct
isoforms have been found for this gene.
Background References:
- Arbogast, S., et al. Ann. Neurol. 65(6):677-686(2009)
- Maiti, B., et al. Hum. Mutat. 30(3):411-416(2009)
- Jurynec, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(34):12485-12490(2008)
- Lin, L., et al. PLoS Genet.(10), E1000225 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SEPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human SEPN1.
NCBI Gene ID #:
57190
NCBI Official Name:
Selenoprotein N
NCBI Official Symbol:
SEPN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
Q9NZV5
Protein GI Number:
317373588
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NZV5
User NOte:
Optimal dilutions for each application to be determined by the researcher.