CCDC50 Antibody
| Code | Size | Price |
|---|
| PSI-57-583-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Coiled-coil domain-containing protein 50, Protein Ymer, CCDC50, C3orf6
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a soluble, cytoplasmic,
tyrosine-phosphorylated protein with multiple ubiquitin-interacting
domains. Mutations in this gene cause nonsyndromic, postlingual,
progressive sensorineural DFNA44 hearing loss. In mouse, the
protein is expressed in the inner ear during development and
postnatal maturation and associates with microtubule-based
structures. This protein may also function as a negative regulator
of NF-kB signaling and as an effector of epidermal growth factor
(EGF)-mediated cell signaling. Alternative splicing results in
multiple transcript variants encoding distinct isoforms. [provided
by RefSeq].
Background References:
- Farfsing, A., et al. Leukemia 23(11):2018-2026(2009)
- Kameda, H., et al. Biochem. Biophys. Res. Commun. 378(4):744-749(2009)
- Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
- Modamio-Hoybjor, S., et al. Am. J. Hum. Genet. 80(6):1076-1089(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CCDC50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human CCDC50.
NCBI Gene ID #:
152137
NCBI Official Name:
Coiled-coil domain-containing protein 50
NCBI Official Symbol:
CCDC50
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q8IVM0
Protein GI Number:
73619722
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8IVM0
User NOte:
Optimal dilutions for each application to be determined by the researcher.