G3BP1 Antibody
| Code | Size | Price |
|---|
| PSI-57-271-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ras GTPase-activating protein-binding protein 1, G3BP-1, ATP-dependent DNA helicase VIII, hDH VIII, GAP SH3 domain-binding protein 1, G3BP1, G3BP
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes one of the DNA-unwinding enzymes which
prefers partially unwound 3'-tailed substrates and can also unwind
partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion.
This enzyme is a member of the heterogeneous nuclear RNA-binding
proteins and is also an element of the Ras signal transduction
pathway. It binds specifically to the Ras-GTPase-activating protein
by associating with its SH3 domain. Several alternatively spliced
transcript variants of this gene have been described, but the
full-length nature of some of these variants has not been
determined.
Background References:
- Gao, X., et al. FEBS Lett. 584(16):3525-3532(2010)
- Ortega, A.D., et al. J. Cell. Sci. 123 (PT 16), 2685-2696 (2010) :
- Hinton, S.D., et al. Biochem. J. 427(3):349-357(2010)
- Shim, J.H., et al. Cancer Prev Res (Phila) 3(5):670-679(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This G3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human G3BP1.
NCBI Gene ID #:
10146
NCBI Official Name:
Ras GTPase-activating protein-binding protein 1
NCBI Official Symbol:
G3BP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q13283
Protein GI Number:
14916572
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q13283
User NOte:
Optimal dilutions for each application to be determined by the researcher.