ANKRD6 Antibody

ProSci
Product Code: PSI-56-807
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-807-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
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ANKRD6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western Blot at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
ANKRD6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Ankyrin repeat domain-containing protein 6, Diversin, ANKRD6, KIAA0957
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
ANKRD6 recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals (By similarity).
Background References:
  • Haribaskar, R., et al. Biochem. Biophys. Res. Commun. 387(1):212-217(2009)
  • Miyasaka, K.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104(27):11274-11279(2007)
  • Schwarz-Romond, T., et al. Genes Dev. 16(16):2073-2084(2002)
  • Tissir, F., et al. Dev. Dyn. 224(4):465-469(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ANKRD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human ANKRD6.
NCBI Gene ID #:
22881
NCBI Official Name:
Ankyrin repeat domain-containing protein 6
NCBI Official Symbol:
ANKRD6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
Q9Y2G4
Protein GI Number:
327478595
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9Y2G4
User NOte:
Optimal dilutions for each application to be determined by the researcher.