WDR12 Antibody
Code | Size | Price |
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PSI-56-836-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}, WD repeat-containing protein 12 {ECO:0000255|HAMAP-Rule:MF_03029}, WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the WD repeat protein
family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),
which may facilitate formation of heterotrimeric or multiprotein
complexes. Members of this family are involved in a variety of
cellular processes, including cell cycle progression, signal
transduction, apoptosis, and gene regulation. This protein is
highly similar to the mouse WD repeat domain 12 protein at the
amino acid level. The protein encoded by this gene is a component
of a nucleolar protein complex that affects maturation of the large
ribosomal subunit.
Background References:
- Kathiresan, S., et al. Nat. Genet. 41(3):334-341(2009)
- Rohrmoser, M., et al. Mol. Cell. Biol. 27(10):3682-3694(2007)
- Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
- Grimm, T., et al. Nucleic Acids Res. 34(10):3030-3043(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This WDR12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human WDR12.
NCBI Gene ID #:
55759
NCBI Official Name:
Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}
NCBI Official Symbol:
WDR12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q9GZL7
Protein GI Number:
20140802
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9GZL7
User NOte:
Optimal dilutions for each application to be determined by the researcher.