PPRC1 Antibody
| Code | Size | Price |
|---|
| PSI-55-559-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1, PGC-1-related coactivator, PRC, PPRC1, KIAA0595
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is similar to PPAR-gamma
coactivator 1 (PPARGC1/PGC-1), a protein that can activate
mitochondrial biogenesis in part through a direct interaction with
nuclear respiratory factor 1 (NRF1). This protein has been shown to
interact with NRF1. It is thought to be a functional relative of
PPARGC1 that activates mitochondrial biogenesis through NRF1 in
response to proliferative signals.
Background References:
- Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
- Vercauteren, K., et al. J. Biol. Chem. 284(4):2307-2319(2009)
- Raharijaona, M., et al. PLoS ONE(11), E7964 (2009) :
- Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PPRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1636-1664 amino acids from the C-terminal region of human PPRC1.
NCBI Gene ID #:
23082
NCBI Official Name:
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
NCBI Official Symbol:
PPRC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
178 kDa
Protein Accession #:
Q5VV67
Protein GI Number:
74756889
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q5VV67
User NOte:
Optimal dilutions for each application to be determined by the researcher.