RSPO4 Antibody
Code | Size | Price |
---|
PSI-62-016-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
R-spondin-4, Roof plate-specific spondin-4, hRspo4, RSPO4, C20orf182
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
RSPO4 is a member of the R-spondin family of
proteins that share a common domain organization consisting of a
signal peptide, cysteine-rich/furin-like domain, thrombospondin
domain and a C-terminal basic region. The encoded protein may be
involved in activation of Wnt/beta-catenin signaling pathways.
Mutations in this gene are associated with anonychia congenital.
Alternate splicing results in multiple transcript variants.
Background References:
- Bergmann, C., et al. Am. J. Hum. Genet. 79(6):1105-1109(2006)
- Blaydon, D.C., et al. Nat. Genet. 38(11):1245-1247(2006)
- Kim, K.A., et al. Cell Cycle 5(1):23-26(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RSPO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the C-terminal region of human RSPO4.
NCBI Gene ID #:
343637
NCBI Official Name:
R-spondin-4
NCBI Official Symbol:
RSPO4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q2I0M5
Protein GI Number:
97189858
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q2I0M5
User NOte:
Optimal dilutions for each application to be determined by the researcher.