RING1 Antibody
| Code | Size | Price |
|---|
| PSI-57-819-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase RING1, 632-, Polycomb complex protein RING1, RING finger protein 1, Really interesting new gene 1 protein, RING1, RNF1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the RING finger family, members of
which encode proteins characterized by a RING domain, a
zinc-binding motif related to the zinc finger domain. The gene
product can bind DNA and can act as a transcriptional repressor. It
is associated with the multimeric polycomb group protein complex.
The gene product interacts with the polycomb group proteins BMI1,
EDR1, and CBX4, and colocalizes with these proteins in large
nuclear domains. It interacts with the CBX4 protein via its
glycine-rich C-terminal domain. The gene maps to the HLA class II
region, where it is contiguous with the RING finger genes FABGL and
HKE4.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- de Bie, P., et al. Biochem. Biophys. Res. Commun. 400(3):389-395(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Barcellos, L.F., et al. PLoS Genet.(10), E1000696 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This RING1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human RING1.
NCBI Gene ID #:
6015
NCBI Official Name:
E3 ubiquitin-protein ligase RING1
NCBI Official Symbol:
RING1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q06587
Protein GI Number:
90110053
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q06587
User NOte:
Optimal dilutions for each application to be determined by the researcher.