PKNOX2 Antibody
| Code | Size | Price |
|---|
| PSI-59-874-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein PKNOX2, Homeobox protein PREP-2, PBX/knotted homeobox 2, PKNOX2, PREP2
Application Note:
For WB starting dilution is: 1:1000
Background:
Homeodomain proteins are sequence-specific transcription
factors that share a highly conserved DNA-binding domain and play
fundamental roles in cell proliferation, differentiation, and
death. PKNOX2 belongs to the TALE (3-amino acid loop extension)
class of homeodomain proteins characterized by a 3-amino acid
extension between alpha helices 1 and 2 within the homeodomain
(Imoto et al., 2001 [PubMed 11549286]).
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. (2009) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PKNOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-324 amino acids from the Central region of human PKNOX2.
NCBI Gene ID #:
63876
NCBI Official Name:
Homeobox protein PKNOX2
NCBI Official Symbol:
PKNOX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q96KN3
Protein GI Number:
115311621
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96KN3
User NOte:
Optimal dilutions for each application to be determined by the researcher.