MXD3 Antibody
Code | Size | Price |
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PSI-58-274-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Max dimerization protein 3, Max dimerizer 3, Class C basic helix-loop-helix protein 13, bHLHc13, Max-associated protein 3, Max-interacting transcriptional repressor MAD3, Myx, MXD3, BHLHC13, MAD3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the Myc superfamily of basic
helix-loop-helix leucine zipper transcriptional regulators. The
encoded protein forms a heterodimer with the cofactor MAX which
binds specific E-box DNA motifs in the promoters of target genes
and regulates their transcription. Disruption of the MAX-MXD3
complex is associated with uncontrolled cell proliferation and
tumorigenesis. Transcript variants of this gene encoding different
isoforms have been described.
Background References:
- Barisone, G.A., et al. Cell Cycle 7(4):423-427(2008)
- Yun, J.S., et al. Mol. Cell. Biol. 27(23):8178-8189(2007)
- Hurlin, P.J., et al. Semin. Cancer Biol. 16(4):265-274(2006)
- Sommer, A., et al. J. Biol. Chem. 273(12):6632-6642(1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MXD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human MXD3.
NCBI Gene ID #:
83463
NCBI Official Name:
Max dimerization protein 3
NCBI Official Symbol:
MXD3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q9BW11
Protein GI Number:
74733390
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9BW11
User NOte:
Optimal dilutions for each application to be determined by the researcher.