GTF3C2 Antibody

ProSci
Product Code: PSI-58-356
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-356-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HL-60 cell line lysates (35ug/lane).

Western blot analysis in HL-60 cell line lysates (35ug/lane).

Further Information

Additional Names:
General transcription factor 3C polypeptide 2, TF3C-beta, Transcription factor IIIC 110 kDa subunit, TFIIIC 110 kDa subunit, TFIIIC110, Transcription factor IIIC subunit beta, GTF3C2, KIAA0011
Application Note:
For WB starting dilution is: 1:1000
Background:
GTF3C2 is required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.
Background References:
  • Dumay-Odelot, H., et al. J. Biol. Chem. 282(23):17179-17189(2007)
  • Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GTF3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the N-terminal region of human GTF3C2.
NCBI Gene ID #:
2976
NCBI Official Name:
General transcription factor 3C polypeptide 2
NCBI Official Symbol:
GTF3C2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
101 kDa
Protein Accession #:
Q8WUA4
Protein GI Number:
48428661
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8WUA4
User NOte:
Optimal dilutions for each application to be determined by the researcher.