ONECUT2 Antibody

ProSci
Product Code: PSI-59-140
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-140-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
Background References:
  • Furuno, K., et al. Genes Immun. 9(4):302-308(2008)
  • Pike, B.L., et al. Leukemia 22(5):1035-1043(2008)
  • Rauch, T., et al. Cancer Res. 66(16):7939-7947(2006)
  • Jacquemin, P., et al. Biochem. Biophys. Res. Commun. 285(5):1200-1205(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ONECUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human ONECUT2.
NCBI Gene ID #:
9480
NCBI Official Name:
One cut domain family member 2
NCBI Official Symbol:
ONECUT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
O95948
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O95948
User NOte:
Optimal dilutions for each application to be determined by the researcher.