ATF4 Antibody
| Code | Size | Price |
|---|
| PSI-62-224-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tax-responsive enhancer element B67; ATF4 protein
Application Note:
For WB starting dilution is: 1:1000
Background:
ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). ATF4 belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Background References:
- Gombart,A.F., J. Leukoc. Biol. 81 (6), 1535-1547 (2007)
- Jousse,C., J. Biol. Chem. 282 (21), 15851-15861 (2007)
- Kakiuchi,C., Neurosci. Lett. 417 (3), 316-321 (2007)
- Marchand,A., J. Biol. Chem. 281 (28), 19124-19133 (2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ATF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-252 amino acids from human ATF4.
NCBI Gene ID #:
468
NCBI Official Name:
ATF4 protein
NCBI Official Symbol:
ATF4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q96AQ3
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96AQ3
User NOte:
Optimal dilutions for each application to be determined by the researcher.