XRCC4 Antibody
Code | Size | Price |
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PSI-60-188-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene functions together with
DNA ligase IV and the DNA-dependent protein kinase in the repair of
DNA double-strand break by non-homologous end joining and the
completion of V(D)J recombination events. The non-homologous
end-joining pathway is required both for normal development and for
suppression of tumors. This gene functionally complements XR-1
Chinese hamster ovary cell mutant, which is impaired in DNA
double-strand breaks produced by ionizing radiation and restriction
enzymes. Alternative transcription initiation and alternative
splicing generates several transcript variants. [provided by
RefSeq].
Background References:
- Gomes, B.C., et al. Oncol. Rep. 24(4):1079-1085(2010)
- Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010)
- Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
- Liu, N., et al. Wei Sheng Yan Jiu 39(4):407-411(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This XRCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human XRCC4.
NCBI Gene ID #:
7518
NCBI Official Name:
DNA repair protein XRCC4
NCBI Official Symbol:
XRCC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q13426
Protein GI Number:
44888352
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q13426
User NOte:
Optimal dilutions for each application to be determined by the researcher.