DDX21 Antibody
| Code | Size | Price |
|---|
| PSI-59-054-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nucleolar RNA helicase 2, DEAD box protein 21, Gu-alpha, Nucleolar RNA helicase Gu, Nucleolar RNA helicase II, RH II/Gu, DDX21
Application Note:
For WB starting dilution is: 1:2000
Background:
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
which is an antigen recognized by autoimmune antibodies from a
patient with watermelon stomach disease. This protein unwinds
double-stranded RNA, folds single-stranded RNA, and may play
important roles in ribosomal RNA biogenesis, RNA editing, RNA
transport, and general transcription.
Background References:
- Holmstrom, T.H., et al. J. Biol. Chem. 283(11):7046-7053(2008)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DDX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21.
NCBI Gene ID #:
9188
NCBI Official Name:
Nucleolar RNA helicase 2
NCBI Official Symbol:
DDX21
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
Protein Accession #:
Q9NR30
Protein GI Number:
76803555
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NR30
User NOte:
Optimal dilutions for each application to be determined by the researcher.