POLR2E Antibody
| Code | Size | Price |
|---|
| PSI-57-719-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1, DNA-directed RNA polymerase II 23 kDa polypeptide, DNA-directed RNA polymerase II subunit E, RPB5 homolog, XAP4, POLR2E
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the fifth largest subunit of RNA
polymerase II, the polymerase responsible for synthesizing
messenger RNA in eukaryotes. This subunit is shared by the other
two DNA-directed RNA polymerases and is present in two-fold molar
excess over the other polymerase subunits. An interaction between
this subunit and a hepatitis virus transactivating protein has been
demonstrated, suggesting that interaction between transcriptional
activators and the polymerase can occur through this subunit. A
pseudogene is located on chromosome 11.
Background References:
- Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
- Cloutier, P., et al. Methods 48(4):381-386(2009)
- Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This POLR2E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human POLR2E.
NCBI Gene ID #:
5434
NCBI Official Name:
DNA-directed RNA polymerases I, II, and III subunit RPABC1
NCBI Official Symbol:
POLR2E
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P19388
Protein GI Number:
116242767
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P19388
User NOte:
Optimal dilutions for each application to be determined by the researcher.