TRIM27 Antibody
| Code | Size | Price |
|---|
| PSI-58-074-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Zinc finger protein RFP, 632-, RING finger protein 76, Ret finger protein, Tripartite motif-containing protein 27, TRIM27, RFP, RNF76
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the tripartite motif (TRIM)
family. The TRIM motif includes three zinc-binding domains, a RING,
a B-box type 1 and a B-box type 2, and a coiled-coil region. This
protein localizes to the nuclear matrix. It interacts with the
enhancer of polycomb protein and represses gene transcription. It
is also thought to be involved in the differentiation of male germ
cells. Fusion of the N-terminus of this protein with the truncated
C-terminus of the RET gene product has been shown to result in
production of the ret transforming protein.
Background References:
- Johnson, A.D., et al. Nat. Genet. 42(7):608-613(2010)
- Barcellos, L.F., et al. PLoS Genet.(10), E1000696 (2009) :
- Tezel, G.G., et al. Pathol. Res. Pract. 205(6):403-408(2009)
- Li, X., et al. Virology 360(2):419-433(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TRIM27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human TRIM27.
NCBI Gene ID #:
5987
NCBI Official Name:
Zinc finger protein RFP
NCBI Official Symbol:
TRIM27
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
P14373
Protein GI Number:
132517
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P14373
User NOte:
Optimal dilutions for each application to be determined by the researcher.