RLIM Antibody
| Code | Size | Price |
|---|
| PSI-60-843-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase RLIM, 632-, LIM domain-interacting RING finger protein, RING finger LIM domain-binding protein, R-LIM, RING finger protein 12, Renal carcinoma antigen NY-REN-43, RLIM, RNF12
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a RING-H2 zinc finger
protein. It has been shown to be an E3 ubiquitin protein ligase
that targets LIM domain binding 1 (LDB1/CLIM), and causes
proteasome-dependent degradation of LDB1. This protein and LDB1 are
co-repressors of LHX1/LIM-1, a homeodomain transcription factor.
Multiple alternatively spliced variants, encoding the same protein,
have been identified.
Background References:
- Jonkers, I., et al. Cell 139(5):999-1011(2009)
- Her, Y.R., et al. J. Biol. Chem. 284(13):8557-8566(2009)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Hiratani, I., et al. Development 130(17):4161-4175(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RLIM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the Central region of human RLIM.
NCBI Gene ID #:
51132
NCBI Official Name:
E3 ubiquitin-protein ligase RLIM
NCBI Official Symbol:
RLIM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
Q9NVW2
Protein GI Number:
143811451
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NVW2
User NOte:
Optimal dilutions for each application to be determined by the researcher.