TCEB3 Antibody
Code | Size | Price |
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PSI-57-554-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Transcription elongation factor B polypeptide 3, Elongin 110 kDa subunit, Elongin-A, EloA, RNA polymerase II transcription factor SIII subunit A1, SIII p110, TCEB3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the protein elongin A, which is a
subunit of the transcription factor B (SIII) complex. The SIII
complex is composed of elongins A/A2, B and C. It activates
elongation by RNA polymerase II by suppressing transient pausing of
the polymerase at many sites within transcription units. Elongin A
functions as the transcriptionally active component of the SIII
complex, whereas elongins B and C are regulatory subunits. Elongin
A2 is specifically expressed in the testis, and capable of forming
a stable complex with elongins B and C. The von Hippel-Lindau tumor
suppressor protein binds to elongins B and C, and thereby inhibits
transcription elongation.
Background References:
- Landa, I., et al. PLoS Genet.(9), E1000637 (2009) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Woo, J.S., et al. EMBO J. 25(6):1353-1363(2006)
- Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TCEB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the Central region of human TCEB3.
NCBI Gene ID #:
6924
NCBI Official Name:
Transcription elongation factor B polypeptide 3
NCBI Official Symbol:
TCEB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
Q14241
Protein GI Number:
294862430
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14241
User NOte:
Optimal dilutions for each application to be determined by the researcher.