PCGF6 Antibody
| Code | Size | Price |
|---|
| PSI-60-168-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene contains a RING finger
motif, which is most closely related to those of polycomb group
(PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to
form protein complexes and function as transcription repressors.
This protein has been shown to interact with some PcG proteins and
act as a transcription repressor. The activity of this protein is
found to be regulated by cell cycle dependent phosphorylation.
Alternatively spliced transcript variants encoding different
isoforms have been identified.
Background References:
- Lee, J.Y., et al. Cancer Res. 68(11):4201-4209(2008)
- Zhang, J., et al. J. Biol. Chem. 283(12):7464-7469(2008)
- Lee, M.G., et al. Cell 128(5):877-887(2007)
- Zhong, N., et al. Biochem. Biophys. Res. Commun. 338(2):855-861(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This PCGF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-217 amino acids from the Central region of human PCGF6.
NCBI Gene ID #:
84108
NCBI Official Name:
Polycomb group RING finger protein 6
NCBI Official Symbol:
PCGF6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q9BYE7
Protein GI Number:
116242703
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9BYE7
User NOte:
Optimal dilutions for each application to be determined by the researcher.