HMGB3 Antibody
| Code | Size | Price |
|---|
| PSI-57-896-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
High mobility group protein B3, High mobility group protein 2a, HMG-2a, High mobility group protein 4, HMG-4, HMGB3, HMG2A, HMG4
Application Note:
For WB starting dilution is: 1:1000
Background:
HMGB3 belongs to the high mobility group (HMG) protein
superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3
contains DNA-binding HMG box domains and is classified into the HMG
box subfamily. Members of the HMG box subfamily are thought to play
a fundamental role in DNA replication, nucleosome assembly and
transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al.,
2006 [PubMed 16945912]).
Background References:
- Nemeth, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(37):13783-13788(2006)
- Ross, M.T., et al. Nature 434(7031):325-337(2005)
- Vaccari, T., et al. Genomics 49(2):247-252(1998)
- Wilke, K., et al. Gene 198 (1-2), 269-274 (1997) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse
Immunogen:
This HMGB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the Central region of human HMGB3.
NCBI Gene ID #:
3149
NCBI Official Name:
High mobility group protein B3
NCBI Official Symbol:
HMGB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
O15347
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O15347
User NOte:
Optimal dilutions for each application to be determined by the researcher.