RFX2 Antibody

ProSci
Product Code: PSI-56-666
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-666-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
DNA-binding protein RFX2, Regulatory factor X 2, RFX2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.
Background References:
  • Purvis, T.L., et al. Gene 460 (1-2), 20-29 (2010) :
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Horvath, G.C., et al. Biol. Reprod. 71(5):1551-1559(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RFX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human RFX2.
NCBI Gene ID #:
5990
NCBI Official Name:
DNA-binding protein RFX2
NCBI Official Symbol:
RFX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
P48378
Protein GI Number:
254763325
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P48378
User NOte:
Optimal dilutions for each application to be determined by the researcher.