GTF2A1L Antibody
| Code | Size | Price |
|---|
| PSI-57-690-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor, GTF2A1L, ALF, GTF2A1LF
Application Note:
For WB starting dilution is: 1:1000
Background:
The assembly and stability of the RNA polymerase II
transcription pre-initiation complex on a eukaryotic core promoter
involve the effects of TFIIA on the interaction between
TATA-binding protein (TBP) and DNA. This gene encodes a germ
cell-specific counterpart of the large (alpha/beta) subunit of
general transcription factor TFIIA that is able to stabilize the
binding of TBP to DNA and may be uniquely important to testis
biology. Alternative splicing for this locus has been observed and
two variants, encoding distinct isoforms, have been identified.
Co-transcription of this gene and the neighboring upstream gene
generates a rare transcript (SALF), which encodes a fusion protein
comprised of sequence sharing identity with each individual gene
product.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Kim, M., et al. J. Biol. Chem. 281(45):34288-34298(2006)
- Howe, M.L., et al. Stem Cells Dev. 15(2):175-190(2006)
- Huang, M., et al. Int. J. Mol. Med. 17(4):599-604(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This GTF2A1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human GTF2A1L.
NCBI Gene ID #:
11036
NCBI Official Name:
TFIIA-alpha and beta-like factor
NCBI Official Symbol:
GTF2A1L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q9UNN4
Protein GI Number:
327478545
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9UNN4
User NOte:
Optimal dilutions for each application to be determined by the researcher.