LCOR Antibody

ProSci
Product Code: PSI-55-165
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-165-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Y79 cell line lysates (35ug/lane).

Western blot analysis in Y79 cell line lysates (35ug/lane).

Further Information

Additional Names:
Ligand-dependent corepressor, LCoR, Mblk1-related protein 2, LCOR, KIAA1795, MLR2
Application Note:
For WB starting dilution is: 1:1000
Background:
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Palijan, A., et al. J. Biol. Chem. 284(44):30275-30287(2009)
  • Palijan, A., et al. J. Biol. Chem. 284(44):30264-30274(2009)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This LCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human LCOR.
NCBI Gene ID #:
84458
NCBI Official Name:
Ligand-dependent corepressor
NCBI Official Symbol:
LCOR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q96JN0
Protein GI Number:
108936028
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96JN0
User NOte:
Optimal dilutions for each application to be determined by the researcher.