SSX3 Antibody

ProSci
Product Code: PSI-59-853
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-853-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Protein SSX3, Cancer/testis antigen 53, CT53, SSX3
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
Background References:
  • Ross, M.T., et al. Nature 434(7031):325-337(2005)
  • Gure, A.O., et al. Int. J. Cancer 101(5):448-453(2002)
  • de Bruijn, D.R., et al. Genes Chromosomes Cancer 34(3):285-298(2002)
  • Gure, A.O., et al. Int. J. Cancer 72(6):965-971(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.
NCBI Gene ID #:
10214
NCBI Official Name:
Protein SSX3
NCBI Official Symbol:
SSX3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q99909
Protein GI Number:
84028266
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q99909
User NOte:
Optimal dilutions for each application to be determined by the researcher.