WTAP Antibody

ProSci
Product Code: PSI-58-781
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-781-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).

Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Pre-mRNA-splicing regulator WTAP, Female-lethal(2)D homolog, hFL(2)D, WT1-associated protein, Wilms tumor 1-associating protein, WTAP, KIAA0105
Application Note:
For WB starting dilution is: 1:1000
Background:
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform.
Background References:
  • Su, J., et al. Diabetes Res. Clin. Pract. 87(2):167-175(2010)
  • Small, T.W., et al. J. Biol. Chem. 284(37):24684-24695(2009)
  • Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009)
  • Zhong, S., et al. Plant Cell 20(5):1278-1288(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This WTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human WTAP.
NCBI Gene ID #:
9589
NCBI Official Name:
Pre-mRNA-splicing regulator WTAP
NCBI Official Symbol:
WTAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q15007
Protein GI Number:
47117889
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15007
User NOte:
Optimal dilutions for each application to be determined by the researcher.