HOXD11 Antibody
| Code | Size | Price |
|---|
| PSI-58-287-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein Hox-D11, Homeobox protein Hox-4F, HOXD11, HOX4F
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the homeobox family of genes. The
homeobox genes encode a highly conserved family of transcription
factors that play an important role in morphogenesis in all
multicellular organisms. Mammals possess four similar homeobox gene
clusters, HOXA, HOXB, HOXC and HOXD, located on different
chromosomes, consisting of 9 to 11 genes arranged in tandem. This
gene is one of several homeobox HOXD genes located in a cluster on
chromosome 2. Deletions that remove the entire HOXD gene cluster or
the 5' end of this cluster have been associated with severe limb
and genital abnormalities. The product of the mouse Hoxd11 gene
plays a role in forelimb morphogenesis.
Background References:
- Sugie, Y., et al. Brain Dev. 32(5):356-361(2010)
- Woo, C.J., et al. Cell 140(1):99-110(2010)
- Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :
- Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HOXD11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human HOXD11.
NCBI Gene ID #:
3237
NCBI Official Name:
Homeobox protein Hox-D11
NCBI Official Symbol:
HOXD11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
P31277
Protein GI Number:
223590220
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P31277
User NOte:
Optimal dilutions for each application to be determined by the researcher.