PPAN Antibody
| Code | Size | Price |
|---|
| PSI-57-374-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homolog, PPAN, BXDC3, SSF1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an evolutionarily
conserved protein similar to yeast SSF1 as well as to the gene
product of the Drosophila gene peter pan (ppan). SSF1 is known to
be involved in the second step of mRNA splicing. Both SSF1 and ppan
are essential for cell growth and proliferation. Exogenous
expression of this gene was reported to reduce the
anchorage-independent growth of some tumor cells. Read-through
transcription of this gene with P2RY11/P2Y(11), an adjacent
downstream gene that encodes an ATP receptor, has been found. These
read-through transcripts are ubiquitously present and up-regulated
during granulocyte differentiation.
Background References:
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
- Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human PPAN.
NCBI Gene ID #:
56342, 692312
NCBI Official Name:
Suppressor of SWI4 1 homolog
NCBI Official Symbol:
PPAN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q9NQ55
Protein GI Number:
21264056
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NQ55
User NOte:
Optimal dilutions for each application to be determined by the researcher.