GTF3A Antibody

ProSci
Product Code: PSI-60-057
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-057-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).

Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Transcription factor IIIA, TFIIIA, GTF3A
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq].
Background References:
  • Wu, C., et al. Proteomics 7(11):1775-1785(2007)
  • Newton-Cheh, C., et al. BMC Med. Genet.SUPPL 1, S7 (2007) :
  • Weser, S., et al. Nucleic Acids Res. 31(9):2408-2416(2003)
  • Hanas, J.S., et al. Gene 282 (1-2), 43-52 (2002) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GTF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-334 amino acids from the C-terminal region of human GTF3A.
NCBI Gene ID #:
2971
NCBI Official Name:
Transcription factor IIIA
NCBI Official Symbol:
GTF3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q92664
Protein GI Number:
172045838
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q92664
User NOte:
Optimal dilutions for each application to be determined by the researcher.