KHDRBS3 Antibody
| Code | Size | Price |
|---|
| PSI-60-293-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
KH domain-containing, RNA-binding, signal transduction-associated protein 3, RNA-binding protein T-Star, Sam68-like mammalian protein 2, SLM-2, Sam68-like phosphotyrosine protein, KHDRBS3, SALP, SLM2
Application Note:
For WB starting dilution is: 1:1000
Background:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression.
Background References:
- Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
- Lu, Y., et al. PLoS ONE(7), E6159 (2009) :
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Schymick, J.C., et al. Lancet Neurol 6(4):322-328(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KHDRBS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the N-terminal region of human KHDRBS3.
NCBI Gene ID #:
10656
NCBI Official Name:
KH domain-containing, RNA-binding, signal transduction-associated protein 3
NCBI Official Symbol:
KHDRBS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
O75525
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75525
User NOte:
Optimal dilutions for each application to be determined by the researcher.