SP3 Antibody
| Code | Size | Price |
|---|
| PSI-57-717-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription factor Sp3, SPR-2, SP3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to a family of Sp1 related genes that
encode transcription factors that regulate transcription by binding
to consensus GC- and GT-box regulatory elements in target genes.
This protein contains a zinc finger DNA-binding domain and several
transactivation domains, and has been reported to function as a
bifunctional transcription factor that either stimulates or
represses the transcription of numerous genes. Transcript variants
encoding different isoforms have been described for this gene, and
one has been reported to initiate translation from a non-AUG (AUA)
start codon. Additional isoforms, resulting from the use of
alternate downstream translation initiation sites, have also been
noted. A related pseudogene has been identified on chromosome 13.
Background References:
- Yamaguchi, K., et al. Biochem. J. 430(1):107-117(2010)
- Jutooru, I., et al. J. Biol. Chem. 285(33):25332-25344(2010)
- Markovics, J.A., et al. J. Biol. Chem. 285(32):24695-24706(2010)
- Eckerstorfer, P., et al. Mol. Immunol. 47 (11-12), 2094-2102 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the Central region of human SP3.
NCBI Gene ID #:
6670
NCBI Official Name:
Transcription factor Sp3
NCBI Official Symbol:
SP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
Q02447
Protein GI Number:
30923147
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q02447
User NOte:
Optimal dilutions for each application to be determined by the researcher.