HOXD4 Antibody
| Code | Size | Price |
|---|
| PSI-58-503-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein Hox-D4, Homeobox protein HHOC13, Homeobox protein Hox-4B, Homeobox protein Hox-51, HOXD4, HOX4B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the homeobox family of genes. The
homeobox genes encode a highly conserved family of transcription
factors that play an important role in morphogenesis in all
multicellular organisms. Mammals possess four similar homeobox gene
clusters, HOXA, HOXB, HOXC and HOXD, located on different
chromosomes, consisting of 9 to 11 genes arranged in tandem. This
gene is one of several homeobox HOXD genes located at 2q31-2q37
chromosome regions. Deletions that removed the entire HOXD gene
cluster or 5' end of this cluster have been associated with severe
limb and genital abnormalities. The protein encoded by this gene
may play a role in determining positional values in developing limb
buds. Alternatively spliced variants have been described but their
full length nature has not been determined.
Background References:
- Zhang, H., et al. Acta Pharmacol. Sin. 31(8):977-983(2010)
- Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :
- Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
- Tan, Y., et al. BMC Mol. Biol. 10, 12 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This HOXD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human HOXD4.
NCBI Gene ID #:
3233
NCBI Official Name:
Homeobox protein Hox-D4
NCBI Official Symbol:
HOXD4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P09016
Protein GI Number:
20141491
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P09016
User NOte:
Optimal dilutions for each application to be determined by the researcher.