CC2D1A Antibody
| Code | Size | Price |
|---|
| PSI-58-358-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Coiled-coil and C2 domain-containing protein 1A, Akt kinase-interacting protein 1, Five prime repressor element under dual repression-binding protein 1, FRE under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N, CC2D1A, AKI1
Application Note:
For WB starting dilution is: 1:1000
Background:
CC2D1A is a transcriptional repressor that binds
to a conserved 14-bp 5'-repressor element and regulates expression
of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal
cells. The DNA binding and transcriptional repressor activities of
the protein are inhibited by calcium. A mutation in this gene
results in nonsyndromic mental retardation-3.
Background References:
- Zhao, M., et al. J. Biol. Chem. 285(32):24372-24380(2010)
- Nakamura, A., et al. Biochem. Biophys. Res. Commun. 393(4):872-876(2010)
- Nakamura, A., et al. J. Cell Biol. 187(5):607-614(2009)
- McKay, G.J., et al. Invest. Ophthalmol. Vis. Sci. 50(2):533-539(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CC2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CC2D1A.
NCBI Gene ID #:
54862
NCBI Official Name:
Coiled-coil and C2 domain-containing protein 1A
NCBI Official Symbol:
CC2D1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
104 kDa
Protein Accession #:
Q6P1N0
Protein GI Number:
74737148
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q6P1N0
User NOte:
Optimal dilutions for each application to be determined by the researcher.