TH1L Antibody

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ProSci
Product Code: PSI-59-052
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-052-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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Further Information

Additional Names:
Negative elongation factor C/D, NELF-C/D, TH1-like protein, NELFCD, NELFD, TH1, TH1L
Application Note:
For WB starting dilution is: 1:1000
Background:
The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.
Background References:
  • Zou, W., et al. Cancer Sci. 101(10):2156-2162(2010)
  • Yang, Y., et al. J. Cell. Biochem. 109(5):1013-1024(2010)
  • Sun, J., et al. J. Biol. Chem. 285(9):6443-6452(2010)
  • Pal, P., et al. Croat. Med. J. 50(4):361-369(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This TH1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-576 amino acids from the C-terminal region of human TH1L.
NCBI Gene ID #:
51497
NCBI Official Name:
Negative elongation factor C/D
NCBI Official Symbol:
NELFCD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
Q8IXH7
Protein GI Number:
38372376
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8IXH7
User NOte:
Optimal dilutions for each application to be determined by the researcher.