WARS Antibody
| Code | Size | Price |
|---|
| PSI-59-659-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tryptophan--tRNA ligase, cytoplasmic, Interferon-induced protein 53, IFP53, Tryptophanyl-tRNA synthetase, TrpRS, hWRS, T1-TrpRS, T2-TrpRS, WARS, IFI53, WRS
Application Note:
For WB starting dilution is: 1:1000
Background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of
tRNA by their cognate amino acid. Because of their central role in
linking amino acids with nucleotide triplets contained in tRNAs,
aminoacyl-tRNA synthetases are thought to be among the first
proteins that appeared in evolution. Two forms of tryptophanyl-tRNA
synthetase exist, a cytoplasmic form, named WARS, and a
mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase
(WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan
and is induced by interferon. Tryptophanyl-tRNA synthetase belongs
to the class I tRNA synthetase family. Four transcript variants
encoding two different isoforms have been found for this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Bhattacharyya, M., et al. Proteins 78(3):506-517(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Ghanipour, A., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):2949-2956(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This WARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-458 amino acids from the C-terminal region of human WARS.
NCBI Gene ID #:
7453
NCBI Official Name:
Tryptophan--tRNA ligase, cytoplasmic
NCBI Official Symbol:
WARS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P23381
Protein GI Number:
135191
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P23381
User NOte:
Optimal dilutions for each application to be determined by the researcher.