HNRNPH2 Antibody
| Code | Size | Price |
|---|
| PSI-57-079-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Heterogeneous nuclear ribonucleoprotein H2, hnRNP H2, FTP-3, Heterogeneous nuclear ribonucleoprotein H', hnRNP H', Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, HNRNPH2, FTP3, HNRPH2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene has three
repeats of quasi-RRM domains that binds to RNAs. It is very similar
to the family member HNRPH1. This gene is thought to be involved in
Fabray disease and X-linked agammaglobulinemia phenotype.
Alternative splicing results in multiple transcript variants
encoding the same protein.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28(23):7050-7065(2008)
- Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine
Immunogen:
This HNRNPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human HNRNPH2.
NCBI Gene ID #:
3188
NCBI Official Name:
Heterogeneous nuclear ribonucleoprotein H2
NCBI Official Symbol:
HNRNPH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
P55795
Protein GI Number:
2500576
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P55795
User NOte:
Optimal dilutions for each application to be determined by the researcher.