FANCB Antibody
| Code | Size | Price |
|---|
| PSI-59-611-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Fanconi anemia group B protein, Protein FACB, Fanconi anemia-associated polypeptide of 95 kDa, FAAP95, FANCB
Application Note:
For WB starting dilution is: 1:1000
Background:
The Fanconi anemia complementation group (FANC) currently
includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2,
FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM
and FANCN (also called PALB2). The previously defined group FANCH
is the same as FANCA. Fanconi anemia is a genetically heterogeneous
recessive disorder characterized by cytogenetic instability,
hypersensitivity to DNA crosslinking agents, increased chromosomal
breakage, and defective DNA repair. The members of the Fanconi
anemia complementation group do not share sequence similarity; they
are related by their assembly into a common nuclear protein
complex. This gene encodes the protein for complementation group B.
Alternative splicing results in two transcript variants encoding
the same protein.
Background References:
- Cheung, K.L., et al. WorldSurg Oncol 8, 38 (2010) :
- Smith, I.M., et al. ORL J. Otorhinolaryngol. Relat. Spec. 72(1):44-50(2010)
- Barroso, E., et al. Breast Cancer Res. Treat. 118(3):655-660(2009)
- Garcia, M.J., et al. Breast Cancer Res. Treat. 113(3):545-551(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FANCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human FANCB.
NCBI Gene ID #:
2187
NCBI Official Name:
Fanconi anemia group B protein
NCBI Official Symbol:
FANCB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
98 kDa
Protein Accession #:
Q8NB91
Protein GI Number:
74751163
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8NB91
User NOte:
Optimal dilutions for each application to be determined by the researcher.