RCN1 Antibody

ProSci
Product Code: PSI-58-698
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-698-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in A375 cell line lysates (35ug/lane).

Western blot analysis in A375 cell line lysates (35ug/lane).

Further Information

Additional Names:
Reticulocalbin-1, RCN1, RCN
Application Note:
For WB starting dilution is: 1:1000
Background:
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
Background References:
  • Favor, J., et al. Genetics 182(4):1077-1088(2009)
  • Hansen, G.A., et al. Mol. Cell. Biochem. 320 (1-2), 25-33 (2009) :
  • Cooper, C.R., et al. J. Cell. Biochem. 104(6):2298-2309(2008)
  • Lim, J., et al. Cell 125(4):801-814(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This RCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-331 amino acids from the C-terminal region of human RCN1.
NCBI Gene ID #:
5954
NCBI Official Name:
Reticulocalbin-1
NCBI Official Symbol:
RCN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q15293
Protein GI Number:
2493462
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15293
User NOte:
Optimal dilutions for each application to be determined by the researcher.